Package index

Dose optimization functions

poso_dose_auc()

Estimate the dose needed to reach a target area under the concentration-time curve (AUC)

poso_dose_conc()

Estimate the optimal dose to achieve a target concentration at any given time

poso_time_cmin()

Estimate the time required to reach a target trough concentration (Cmin)

poso_inter_cmin()

Estimate the optimal dosing interval to consistently achieve a target trough concentration (Cmin)

Estimation functions

Functions for estimating the pharmacokinetic parameters

poso_estim_map()

Estimate the Maximum A Posteriori individual parameters

poso_estim_mcmc()

Estimate the posterior distribution of individual parameters by MCMC

poso_estim_sir()

Estimate the posterior distribution of individual parameters by SIR

poso_simu_pop()

Estimate the prior distribution of population parameters